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Background
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MOGT2 catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. It exhibits a preference toward monoacylglycerols containing unsaturated fatty acids in the order of C18:3 > C18:2 > C18:1 > C18:0. This protein plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. MOGT2 may play a role in diet-induced obesity.
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Background
References
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- Cao,J., J. Biol. Chem. 279 (18), 18878-18886 (2004)
- Cao,J., J. Biol. Chem. 278 (28), 25657-25663 (2003)
- Yen,C.L., J. Biol. Chem. 278 (20), 18532-18537 (2003)
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