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Background
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SENP3 releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. This protein deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability.
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Background
References
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- Muller S, et al., Nat Rev Mol Cell Biol. 2001 2(3):202-10 Review.
- Hochstrasser M. Cell. 2001 107(1):5-8. Review.
- Kahyo T, et al., Mol Cell. 2001 Sep;8(3):713-8.
- Yeh ET, et al., Gene. 2000 May 2;248(1-2):1-14. Review.
- Keane,M.M., et al., Oncogene 18 (22), 3365-3375 (1999)
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