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Background
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CIR may modulate splice site selection during alternative splicing of pre-mRNAs. It regulates transcription and acts as corepressor for RBPSUH. It recruits RBPSUH to the Sin3-histone deacetylase complex (HDAC), and is required for RBPSUH-mediated repression of transcription.
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Background
References
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- Olsen,J.V., Cell 127 (3), 635-648 (2006)
- Maita,H., Exp. Cell Res. 303 (2), 375-387 (2005)
- Zhou,S., Mol. Cell. Biol. 21 (18), 6222-6232 (2001)
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