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Background
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Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the ALDH3A2 gene cause Sjogren-Larsson syndrome.
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Background
References
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- Ashibe,B., J. Biol. Chem. 282 (28), 20763-20773 (2007)
- Rizzo,W.B., Mol. Genet. Metab. 90 (1), 1-9 (2007)
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