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Background
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KITLG is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis.
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Background
References
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- Young,S.M., Cell. Signal. 19 (12), 2572-2581 (2007)
- Pick,M., Stem Cells 25 (9), 2206-2214 (2007)
- Yasuda,A., Dig. Dis. Sci. 52 (9), 2292-2300 (2007)
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