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Background
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The visinin and visinin-like peptides represent a family of calcium-binding proteins that are highly expressed in the retina. Visinin has been shown to be a cone cell-specific protein with a molecular weight of 24 kDa. Several members of the visinin family of genes have been isolated and characterized from different species. These peptides are believed to be involved in the processes of phototransduction. The recoverin gene (RCV1) is believed to be involved in the pathophysiology of retinopathy in cancer patients.
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Background
References
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- Braunewell, K.H., et al., Neuropharmacology 44(6):707-715 (2003).
- Lin, L., et al., J. Biol. Chem. 277(44):41872-41878 (2002).
- Spilker, C., et al., J. Neurosci. 22(17):7331-7339 (2002).
- Bernstein, H.G., et al., Neuroreport 13(4):393-396 (2002).
- Lin, L., et al., Biochem. Biophys. Res. Commun. 296(4):827-832 (2002).
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