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Background
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EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with EIF4-F and EIF4-A by binding near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. It also promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F
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Background
References
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- Doepker, R.C., et al., J. Virol. 78(9):4684-4699 (2004).
- Fleming, K., et al., Biochemistry 42(30):8966-8975 (2003).
- Milburn, S.C., et al., EMBO J. 9(9):2783-2790 (1990).
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