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Background
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NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
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Background
References
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- Tanaka, T., et al., J. Biol. Chem. 278(35):32905-32913 (2003).
- Akey, D.T., et al., Hum. Mol. Genet. 11(22):2723-2733 (2002).
- Kito, K., et al., J. Biol. Chem. 276(23):20603-20609 (2001).
- Scanlan, M.J., et al., Int. J. Cancer 83(4):456-464 (1999).
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List Price (USA): $235.00/0.1mg
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