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Background
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PPT2 removes thioester-linked fatty acyl groups from modified cysteine residues in proteins and prefers the acyl groups palmitic and myristic acid over other long-chain acyl substrates. It is a glycosylated lysosomal protein and member of the palmitoyl-protein thioesterase family.
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Background
References
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- Clark, H.F., et al., Genome Res. 13(10):2265-2270 (2003).
- Calero, G., et al., J. Biol. Chem. 278(39):37957-37964 (2003).
- Soyombo, A.A., et al., Genomics 56(2):208-216 (1999).
- Soyombo, A.A., et al., J. Biol. Chem. 272(43):27456-27463 (1997).
- Aguado, B., et al., Biochem. J. 341 (Pt 3), 679-689 (1999).
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