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Background
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Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilin 3 is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane.
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Background
References
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- Kakizawa,S., EMBO J. 26 (7), 1924-1933 (2007)
- Moriguchi,S., Proc. Natl. Acad. Sci. U.S.A. 103 (28), 10811-10816 (2006)
- Nishi,M., Brain Res. Mol. Brain Res. 118 (1-2), 102-110 (2003)
- Nishi,M., Biochem. Biophys. Res. Commun. 292 (2), 318-324 (2002)
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