|
Background
|
Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.
|
Background
References
|
- Gizak,A., Proteins 72 (1), 209-216 (2008)
- Lu,J., Biochem. Biophys. Res. Commun. 369 (3), 948-952 (2008)
- Valis,K., Mol. Cell. Biochem. 311 (1-2), 225-231 (2008)
|
Order Information
List Price (USA): $235.00/0.1mg
Related Products
Data Rewards Program
