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Background
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ZIC3 is a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in the gene encoding ZIC3 cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
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Background
References
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- Zhu,L., Hum. Mutat. 29 (1), 99-105 (2008)
- Zhu,L., Hum. Mol. Genet. 16 (14), 1649-1660 (2007)
- Bedard,J.E., Hum. Mol. Genet. 16 (2), 187-198 (2007)
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List Price (USA): $235.00/0.1mg
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