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Background
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ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells.
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Background
References
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- Cao, C., et al., Biochemistry 42(35):10348-10353 (2003).
- Cao, C., et al., J. Biol. Chem. 278(32):29667-29675 (2003).
- Kruh, G.D., et al., Proc. Natl. Acad. Sci. U.S.A. 87(15):5802-5806 (1990).
- Kruh, G.D., et al., Science 234(4783):1545-1548 (1986).
- Bianchi, C., et al., FEBS Lett. 527 (1-3), 216-222 (2002) (): ().
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