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Background
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This gene for the cJun protein is the putative transforming gene of avian sarcoma virus 17. The protein is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. The gene for this protein is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.
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Background
References
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- Fang, D., et al., Proc. Natl. Acad. Sci. U.S.A. 101(41):14782-14787 (2004).
- Wang, Y., et al., Biochem. Biophys. Res. Commun. 323(1):9-16 (2004).
- Wehkamp, J., et al., Infect. Immun. 72(10):5750-5758 (2004).
- Gensch, E., et al., J. Biol. Chem. 279(37):39085-39093 (2004).
- Fujioka, S., et al., Mol. Cell. Biol. 24(17):7806-7819 (2004).
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