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Background
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Component of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway.
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Background
References
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- Dasse,E., Leukemia 21 (4), 595-603 (2007)
- Yu,F., PLoS Pathog. 3 (3), E44 (2007)
- Wu,Y., Oncogene 25 (42), 5787-5800 (2006)
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