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Background
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MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. This protein controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. It may also be involved in neurogenesis and in the development of cortical architecture.
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Background
References
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- Konig, S., et al., J. Biol. Chem. 279(27):28187-28196 (2004).
- Maeda, T., et al., J. Biol. Chem. 277(50):48889-48898 (2002).
- Maeda, T., et al., Biochem. Biophys. Res. Commun. 294(4):791-797 (2002).
- Janson, C.G., et al., Brain Res. Mol. Brain Res. 97(1):70-82 (2001).
- Krainc, D., et al., Genomics 29(3):809-811 (1995).
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