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Background
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The membrane-associated protein ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
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Background
References
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- Zhang, F., et al., J. Biol. Chem. 275(30):23287-23294 (2000).
- Allikmets, R., et al., Mamm. Genome 6(2):114-117 (1995).
- Zhang, F., et al., FEBS Lett. 478 (1-2), 89-94 (2000).
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