|
Background
|
Present mainly in the mitochondrial compartment of peripheral tissues, the protein BZRP interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis.
|
Background
References
|
- Cosenza-Nashat,M., Neuropathol. Appl. Neurobiol. 35 (3), 306-328 (2009)
- Karry,R., Pharmacogenet. Genomics 18 (11), 977-988 (2008)
|