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Background
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Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals.
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Background
References
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- Schneider,S., J. Biol. Chem. 283 (44), 30064-30072 (2008)
- Qian,Y., Biochem. J. 415 (1), 123-134 (2008)
- Wamelink,M.M., J. Inherit. Metab. Dis. 30 (5), 735-742 (2007)
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