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Background
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GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).
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Background
References
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- Li,Q., Ye,Z. Biochem. Biophys. Res. Commun. 385 (2), 284-289 (2009)
- Walsh,N., Dowling,P. J Proteomics 71 (5), 561-571 (2008)
- Paunio,T., Kiuru,S. Genomics 13 (1), 237-239 (1992)
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