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Background
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Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK is an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation.
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Background
References
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- Yang, T., et al., Biomol. Eng. 19(1):1-4 (2002).
- Togawa, K., et al., J. Cell. Physiol. 183(1):129-139 (2000).
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