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Background
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Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis.
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Background
References
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- Littler, E., et al., EMBO J. 5(8):1959-1966 (1986).
- Bankier, A.T., et al., Mol. Biol. Med. 1(1):21-45 (1983).
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