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Background
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Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma.
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Background
References
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- Binnie, M.C., et al., Prostate 63(4):309-315 (2005).
- Habib, F.K., et al., Int. J. Cancer 114(2):190-194 (2005).
- Laidler, P., et al., Arch. Biochem. Biophys. 435(1):1-14 (2005).
- Dallas, S.L., et al., J. Cell. Physiol. 202(2):361-370 (2005).
- Olsson, A.Y., et al., Genomics 84(1):147-156 (2004).
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List Price (USA): $42.00/0.1mg
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