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Catalog #
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Source:
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Lot #
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Size:
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AM1100a
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Mouse
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SD40504A
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_005420, P49767
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30AT1174.77.260
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Mouse IgG1
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H, M
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46883 Da
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Target/Specificity:
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This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides selected from the N-terminal, central, and C-terminal regions of human VEGF3.
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Other Names:
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Vascular Endothelial Growth Factor C, VEGF-C; Vascular endothelial growth factor-related protein; VRP; Flt4 ligand; Flt4-L; VEGF3
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Application Data:
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Western analysis of extracts from HDMEC cells using VEGF3 antibody. |
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Background:
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VEGF3 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
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Background References:
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- Byeon, J.S., et al., J. Gastroenterol. Hepatol. 19(6):648-654 (2004).
- Su, J.L., et al., Cancer Res. 64(2):554-564 (2004).
- Yan, C., et al., World J. Gastroenterol. 10(6):783-790 (2004).
- Hsieh, C.Y., et al., J. Biomed. Sci. 11(2):249-259 (2004).
- Liu, X.E., et al., World J. Gastroenterol. 10(3):352-355 (2004).
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Product Citations:
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Application Notes:
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| ELISA | 1:1,000 |
| Western blotting | 1:100~500 |
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Format:
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Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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