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Catalog #
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Source:
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Lot #
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Size:
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AM1101a
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Mouse
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SDG051011G
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_004460, O43915
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28AT743.288.48
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Mouse IgG1
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H, M
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40444 Da
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Target/Specificity:
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This monoclonal antibody is generated from mice immunized with three KLH conjugated synthetic peptides corresponding to N-terminal, central, and C-terminal sequences of human VEGF4.
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Other Names:
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Vascular Endothelial Growth Factor D, c-fos-induced growth factor, FIGF, VEGFD, VEGF-D, VEGF4
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Application Data:
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The anti-VEGF4 Mab (Cat. #AM1101a) is used in Western blot to detect VEGF4 in HDMEC cell lysate. |
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Background:
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VEGF4 is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C.
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Background References:
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- Orlandini, M., et al., J. Biol. Chem. 278(45):44650-44656 (2003).
- McColl, B.K., et al., J. Exp. Med. 198(6):863-868 (2003).
- Rissanen, T.T., et al., Circ. Res. 92(10):1098-1106 (2003).
- Nakamura, Y., et al., Clin. Cancer Res. 9(2):716-721 (2003).
- Yokoyama, Y., et al., Br. J. Cancer 88(2):237-244 (2003).
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Product Citations:
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Application Notes:
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| ELISA | 1:1,000 |
| Western blotting | 1:100~500 |
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Format:
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Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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