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Catalog #
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Source:
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Lot #
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Size:
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AP1075a
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Rabbit
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SH040608E
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_114121, Q96T68
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RB5754
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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E
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H
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81854 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human SETDB2.
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Other Names:
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Histone H3-K9 methyltransferase; H3-K9-HMTase; SET domain bifurcated 2; Chronic lymphocytic leukemia deletion region gene 8 protein;
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Application Data:
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This product is offered at a low price as part of the Abgent Product Investigation Program. Additionally, submit your positive data for this or any Abgent antibody to our Data Rewards Program and receive a free gift.
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Background:
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Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity.
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Background References:
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- Zhang, Y., et al., Nat. Genet. 34(2):181-186 (2003).
- Mabuchi, H., et al., Cancer Res. 61(7):2870-2877 (2001).
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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