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Catalog #
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Source:
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Lot #
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Size:
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AP1081b
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Rabbit
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SH040610D
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_006379, Q92993
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RB5777
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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58582 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human HTATIP.
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Other Names:
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60 kDa Tat interactive protein; Tip60; HIV-1 Tat interactive protein; cPLA(2) interacting protein;
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Application Data:
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Western blot analysis of anti-HTATIP Pab (Cat. #AP1081b) in CEM cell line tissue lysate (35ug/lane).HTATIP(arrow) was detected using the purified Pab (1:60 dilution). |
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Background:
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HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.
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Background References:
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- Cai, Y., et al., J. Biol. Chem. 280(14):13665-13670 (2005).
- Patel, J.H., et al., Mol. Cell. Biol. 24(24):10826-10834 (2004).
- Legube, G., et al., J. Biol. Chem. 279(43):44825-44833 (2004).
- Franzese, O., et al., Cell Death Differ. 11(7):782-784 (2004).
- Taubert, S., et al., Mol. Cell. Biol. 24(10):4546-4556 (2004).
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:100~500 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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