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PRDM1 (BLIMP1) Antibody
Purified Rabbit Polyclonal Antibody (Pab)

Catalog # Source: Lot # Size:
AP1201a Rabbit SD020904A 0.1 mg
Concentration: Accession: Clone Name: Isotype:
0.25 mg/ml NP_001189 BUR162 Rabbit Ig
Applications: Reactivity: MW (kDa):
E H 87991 Da
Target/Specificity:
Purified recombinant GST fusion protein encoding N-terminal aa 1-347 of human BLIMP1.
Other Names:
BLIMP1
Application Data:

This product is offered at a low price as part of the Abgent Product Investigation Program. Additionally, submit your positive data for this or any Abgent antibody to our Data Rewards Program and receive a free gift.

Background:
This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. The protein encoded by this transcript has also been named PRDI-BF1alpha.
Background References:
  1. Gyory, I., et al., J. Immunol. 170(6):3125-3133 (2003).
  2. Borson, N.D., et al., Blood 100(13):4629-4639 (2002).
  3. Vasanwala, F.H., et al., J. Immunol. 169(4):1922-1929 (2002).
  4. Shaffer, A.L., et al., Immunity 17(1):51-62 (2002).
  5. Medina, F., et al., Blood 99(6):2154-2161 (2002).
Product Citations:
Application Notes:
The suggested dilution is:
ELISA1:1,000
Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage:
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.