|
Catalog #
|
Source:
|
Lot #
|
Size:
|
|
AP1412c
|
Rabbit
|
SH080202N
|
0.1 mg
|
|
Concentration:
|
Accession:
|
Clone Name:
|
Isotype:
|
|
0.25 mg/ml
|
NP_057066, Q9Y2T7
|
RB13983
|
Rabbit Ig
|
|
Applications:
|
Reactivity:
|
MW (kDa):
|
|
WB, E
|
H
|
38518 Da
|
|
Target/Specificity:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|
|
Other Names:
|
|
Y-box-binding protein 2; Germ cell-specific Y-box-binding protein; Contrin; MSY2 homolog; DNA-binding protein C; Dbpc; CSDA3; MSY2
|
|
Application Data:
|
Western blot analysis of anti-YBX2 Antibody (Center) (RB13983) in Jurkat cell line lysates (35ug/lane). YBX2(arrow) was detected using the purified Pab (1:60 dilution). |
|
|
Background:
|
|
Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
|
|
Background References:
|
- Kohno,Y., Br. J. Cancer 94 (5), 710-716 (2006)
- Yoshida,T., Biochim. Biophys. Acta 1759 (1-2), 80-88 (2006)
- Tekur,S., J. Androl. 20 (1), 135-144 (1999)
- Gu,W., Biol. Reprod. 59 (5), 1266-1274 (1998)
|
|
Product Citations:
|
|
|
|
Application Notes:
|
| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
|
|
Format:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|
|
Storage:
|
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
|
|
Precautions:
|
|
This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
|
