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Catalog #
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Source:
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Lot #
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Size:
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AP1451a
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Rabbit
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SH070920G
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_006259, Q92785
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RB12540
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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44025 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DPF2.
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Other Names:
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REQ; UBID4; ubi-d4; MGC10180
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Application Data:
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(LEFT)Western blot analysis of DPF2 (arrow) using rabbit polyclonal DPF2 Antibody (N-term)(Cat.#AP1451a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the DPF2 gene (Lane 2) (Origene Technologies). (RIGHT)Western blot analysis of anti-DPF2 Antibody (N-term) (Cat.#AP1451a) in T47D cell line lysates (35ug/lane). DPF2 (arrow) was detected using the purified Pab. |
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Background:
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DPF2 is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. DPF2 gene is considered a causal candidate for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
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Background References:
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- Olsen,J.V.,Cell 127 (3), 635-648 (2006)
- Beausoleil,S.A.,Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA 1:1,000 | |
| Western blotting 1:100~500 | |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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