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Catalog #
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Source:
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Lot #
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Size:
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AP1451c
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Rabbit
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SH070823AW
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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Q92785, NP_006259
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RB12370
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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44155 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human DPF2.
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Other Names:
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Zinc finger protein ubi-d4; Requiem; Apoptosis response zinc finger protein; D4, zinc and double PHD fingers family 2; DPF2; REQ; UBID4;
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Application Data:
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Western blot analysis of anti-DPF2 Antibody (Center) (Cat.#AP1451c) in HL60 cell line lysates (35ug/lane). DPF2 (arrow) was detected using the purified antibody. |
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Background:
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DPF2 is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. The DPF2 gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
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Background References:
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- Ninkina, N.N., et al., Mamm. Genome 12(11):862-866 (2001).
- Gabig, T.G., et al., Mamm. Genome 9(8):660-665 (1998).
- Guru, S.C., et al., Genome Res. 7(7):725-735 (1997).
- Chestkov, A.V., et al., Genomics 36(1):174-177 (1996).
- Gabig, T.G., et al., J. Biol. Chem. 269(47):29515-29519 (1994).
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:100~500 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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