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Catalog #
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Source:
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Lot #
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Size:
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AP1493a
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Rabbit
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SA080117AQ
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_001102, P55265
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RB13356
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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135995 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ADAR.
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Other Names:
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Double-stranded RNA-specific adenosine deaminase; DRADA; 136 kDa double-stranded RNA-binding protein; P136; K88DSRBP; Interferon-inducible protein 4; IFI-4; ADAR1; DSRAD; G1P1; IFI4
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Application Data:
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Western blot analysis of ADAR Antibody (N-term) in NCI-H460 cell line lysates (35ug/lane). ADAR(arrow) was detected using the purified Pab (1:60 dilution). |
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Background:
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ADAR is the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double stranded RNA through conversion of adenosine to inosine. Mutations have been associated with dyschromatosis symmetrica hereditaria.
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Background References:
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- Lykke-Andersen,S., RNA 13 (10), 1732-1744 (2007)
- Li,M., Arch. Dermatol. Res. 299 (5-6), 273-275 (2007)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long
term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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