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Catalog #
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Source:
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Lot #
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Size:
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AP1826d
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Rabbit
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SH071113B
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_060219, Q9C0C7
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RB13115
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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IHC, E
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H
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142507 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the ED domain region of human AMBRA1.
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Other Names:
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Activating molecule in BECN1-regulated autophagy protein 1; KIAA1736
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Application Data:
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Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with AMBRA1 antibody (ED domain), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Background:
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AMBRA1 regulates autophagy and development of the nervous system. This protein is involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.
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Background References:
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- Maria Fimia G.,Nature 447:1121-1125(2007).
- Nagase T.,DNA Res. 7:347-355(2000).
- Ota T.,Nat. Genet. 36:40-45(2004).
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Immunohistochemistry | 1:10~50 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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