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Catalog #
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Source:
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Lot #
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Size:
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AP2789b
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Rabbit
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SH081014H
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_000805, P28472
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RB15034
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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54116 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GABRB3.
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Other Names:
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Gamma-aminobutyric acid receptor subunit beta-3; GABA(A) receptor subunit beta-3; GABRB3
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Application Data:
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Western blot analysis of GABRB3 antibody (C-term) (Cat.# AP2789b) in Y79 cell line lysates (35ug/lane). GABRB3 (arrow) was detected using the purified Pab. |
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Background:
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GABRB3 is a member of the ligand-gated ionic channel family. This protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.
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Background References:
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- Vieira,A.R.,Am. J. Med. Genet. A 146A (21), 2828-2830 (2008)
- Russek,S.J., Genomics 23 (3), 528-533 (1994)
- Saitoh,S., Lancet 339 (8789), 366-367 (1992)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at 20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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