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Catalog #
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Source:
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Lot #
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Size:
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AP3508a
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Rabbit
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SA080402AR
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_036472
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RB11197
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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DB, E
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H
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99654 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S326 of human NFATC2.
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Other Names:
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NFAT1; NFATP; KIAA0611
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Application Data:
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Dot blot analysis of anti-Phospho-NFATC2-pS326 Antibody(Cat.#AP3508a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
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Background:
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NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. This protein is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). It is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.
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Background References:
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- Golks,A., EMBO J. 26 (20), 4368-4379 (2007)
- Dong,X., J. Biol. Chem. 282 (41), 30303-30310 (2007)
- Gibson,H.M., J. Immunol. 179 (6), 3831-3840 (2007)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Dot Blot | 1:500 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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