|
Catalog #
|
Source:
|
Lot #
|
Size:
|
|
AP3601a
|
Rabbit
|
SA081204AC
|
0.1 mg
|
|
Concentration:
|
Accession:
|
Clone Name:
|
Isotype:
|
|
0.25 mg/ml
|
NP_005611, P31949
|
RB16255
|
Rabbit Ig
|
|
Applications:
|
Reactivity:
|
MW (kDa):
|
|
DB, E
|
H
|
11740 Da
|
|
Target/Specificity:
|
|
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y32 of human S100A11.
|
|
Other Names:
|
|
Protein S100-A11; S100 calcium-binding protein A11; Protein S100C; Calgizzarin; MLN 70; S100A11; MLN70; S100C
|
|
Application Data:
|
Dot blot analysis of anti-Phospho-S100A11-pY32 Antibody (Cat.#AP3601a) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. |
|
|
Background:
|
|
Protein S100-A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.
|
|
Background References:
|
- Howell,M.D., J. Invest. Dermatol. 128 (9), 2248-2258 (2008)
- Cecil,D.L., J. Immunol. 180 (12), 8378-8385 (2008)
- Sakaguchi,M., J. Cell Biol. 163 (4), 825-835 (2003)
|
|
Product Citations:
|
|
|
|
Application Notes:
|
| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Dot Blot | 1:500 |
|
|
Format:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
|
|
Storage:
|
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
|
|
Precautions:
|
|
This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
|
