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HES1 Antibody (N-term T24)
Purified Rabbit Polyclonal Antibody (Pab)

Catalog # Source: Lot # Size:
AP6276a Rabbit SH080130I 0.1 mg
Concentration: Accession: Clone Name: Isotype:
0.25 mg/ml NP_005515, Q14469 RB13980 Rabbit Ig
Applications: Reactivity: MW (kDa):
WB, E H 29541 Da
Target/Specificity:
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human HES1.
Other Names:
Transcription factor HES-1; Hairy and enhancer of split 1; Hairy-like; HHL; Hairy homolog; HL; HRY
Application Data:
HES1 Antibody (N-term T24)

Western blot analysis of anti-HES1 Antibody (N-term T24) (RB13980) in HL60 cell line lysates (35ug/lane). HES1 (arrow) was detected using the purified Pab (1:60 dilution).

Background:
HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. HES1 has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Background References:
  1. Liu,J., Int. J. Gynecol. Cancer 17 (6), 1293-1299 (2007)
  2. Karlsson,C., J. Orthop. Res. 25 (2), 152-163 (2007)
Product Citations:
Application Notes:
The suggested dilution is:
ELISA1:1,000
Western blotting1:50~100
Format:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage:
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.