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Catalog #
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Source:
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Lot #
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Size:
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AP6606b
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Rabbit
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SH090813AK
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_000705, P30536
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RB19741
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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18779 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BZRP.
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Other Names:
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Translocator protein; Peripheral-type benzodiazepine receptor; PBR; PKBS; Mitochondrial benzodiazepine receptor; MBR; BZRP; TSPO
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Application Data:
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Western blot analysis of BZRP Antibody (C-term) (Cat. #AP6606b) in A375 cell line lysates (35ug/lane). BZRP (arrow) was detected using the purified Pab. |
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Background:
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Present mainly in the mitochondrial compartment of peripheral tissues, the protein BZRP interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis.
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Background References:
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- Cosenza-Nashat,M., Neuropathol. Appl. Neurobiol. 35 (3), 306-328 (2009)
- Karry,R., Pharmacogenet. Genomics 18 (11), 977-988 (2008)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at 20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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