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Catalog #
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Source:
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Lot #
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Size:
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AP6664b
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Rabbit
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SH090803AA
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_005997, Q05516
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RB18799
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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74274 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PLZF.
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Other Names:
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Zinc finger and BTB domain-containing protein 16; Zinc finger protein PLZF; Promyelocytic leukemia zinc finger protein; Zinc finger protein 145; ZNF145; PLZF; ZBTB16
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Application Data:
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Western blot analysis of PLZF antibody (C-term) (Cat. #AP6664b) in K562 cell line lysates (35ug/lane). PLZF (arrow) was detected using the purified Pab. |
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Background:
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PLZF is a member of the Krueppel C2H2-type zinc-finger protein family and a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL).
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Background References:
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- Shi,J., Int. J. Cancer 125 (7), 1558-1565 (2009)
- Doulatov,S., Genes Dev. 23 (17), 2076-2087 (2009)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at 20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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