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Catalog #
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Source:
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Lot #
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Size:
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AP7326b
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Rabbit
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SH090702AH
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_000168, P06396
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RB18722
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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85698 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GSN.
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Other Names:
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Gelsolin; Actin-depolymerizing factor; ADF; Brevin; AGEL; GSN
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Application Data:
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Western blot analysis of GSN antibody (C-term) (Cat.#AP7326b) in A375, A2058 cell line lysates and mouse lung, bladder tissue lysates (35ug/lane). GSN(arrow) was detected using the purified Pab. |
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Background:
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GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).
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Background References:
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- Li,Q., Ye,Z. Biochem. Biophys. Res. Commun. 385 (2), 284-289 (2009)
- Walsh,N., Dowling,P. J Proteomics 71 (5), 561-571 (2008)
- Paunio,T., Kiuru,S. Genomics 13 (1), 237-239 (1992)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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