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Catalog #
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Source:
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Lot #
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Size:
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AP7420b
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Rabbit
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SH080721E
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_004030, P07355
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RB15467
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, IHC, E
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H
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38604 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ANXA2.
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Other Names:
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Annexin A2; Annexin-2; Annexin II; Lipocortin II; Calpactin I heavy chain; Chromobindin-8; p36; Protein I; Placental anticoagulant protein IV; PAP-IV; ANXA2; ANX2; ANX2L4; CAL1H; LPC2D
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Application Data:
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Western blot analysis of anti-ANXA2 Antibody (C-term) (Cat.#AP7420b) in A2058 cell line lysates (35ug/lane). ANXA2(arrow) was detected using the purified Pab. |
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANXA2 antibody (C-term) (Cat.#AP7420b), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Background:
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ANXA2 is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption.
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Background References:
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- He,K.L., J. Biol. Chem. 283 (28), 19192-19200 (2008)
- Tamma,G., Pflugers Arch. 456 (4), 729-736 (2008)
- Gou,D., J. Biol. Chem. 283 (19), 13156-13164 (2008)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
| Immunohistochemistry | 1:10~50 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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