|
Catalog #
|
Source:
|
Lot #
|
Size:
|
|
AP7437a
|
Rabbit
|
SH090408B
|
0.1 mg
|
|
Concentration:
|
Accession:
|
Clone Name:
|
Isotype:
|
|
0.25 mg/ml
|
NP_003807, Q13443
|
RB17776
|
Rabbit Ig
|
|
Applications:
|
Reactivity:
|
MW (kDa):
|
|
WB, E
|
H, M
|
90556 Da
|
|
Target/Specificity:
|
|
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ADAM9.
|
|
Other Names:
|
|
Cellular disintegrin-related protein; Meltrin-gamma; Myeloma cell metalloproteinase; Metalloprotease/disintegrin/cysteine-rich protein 9; A disintegrin and metalloproteinase domain 9; ADAM 9; ADAM9; KIAA0021; MCMP; MDC9; MLTNG
|
|
Application Data:
|
Western blot analysis of anti-ADAM9 Antibody (N-term)(Cat.#AP7437a) in mouse kidney tissue lysates (35ug/lane). ADAM9 (arrow) was detected using the purified Pab. |
|
|
Background:
|
|
ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.
|
|
Background References:
|
- Weskamp G., Kraetzschmar J., Reid M.S.J. Cell Biol. 132:717-726(1996)
- Hotoda N., Koike H.Biochem. Biophys. Res. Commun. 293:800-805(2002)
- McKie N., Edwards T., Dallas D.J.Biochem. Biophys. Res. Commun. 230:335-339(1997)
|
|
Product Citations:
|
|
|
|
Application Notes:
|
| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
|
|
Format:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|
|
Storage:
|
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
|
|
Precautions:
|
|
This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
|