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Catalog #
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Source:
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Lot #
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Size:
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AP7447c
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Rabbit
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SA090410AB
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_008969, Q9UNA0
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RB18038
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H, M
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101716 Da (Cleaves aggrecan at the 392-Glu-|-Ala-393 site)
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human ADAMTS5.
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Other Names:
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A disintegrin and metalloproteinase with thrombospondin motifs 5; Aggrecanase-2; ADMP-2; A disintegrin and metalloproteinase with thrombospondin motifs 11; ADAMTS11, ADMP2
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Application Data:
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Western blot analysis of anti-ADAMTS5 Antibody (Center) (Cat.#AP7447c) in mouse muscle tissue lysates (35ug/lane). ADAMTS5(arrow) was detected using the purified Pab. |
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Background:
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ADAMTS5 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
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Background References:
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- Abbaszade I., Liu R.-Q.J. Biol. Chem. 274:23443-23450(1999)
- Hurskainen T.L., Hirohata S.J. Biol. Chem. 274:25555-25563(1999)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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