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Catalog #
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Source:
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Lot #
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Size:
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AP7477a
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Rabbit
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SH090526E
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_004143, P54368
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RB18521
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H, M
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25406 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human OAZ1.
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Other Names:
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Ornithine decarboxylase antizyme; ODC-Az ; OAZ
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Application Data:
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Western blot analysis of OAZ1 Antibody (N-term) (Cat.#AP7477a) in mouse heart tissue lysates (35ug/lane). OAZ1 (arrow) was detected using the purified Pab. |
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Background:
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OAZ1 catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. This protein play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. The protein expression is auto-regulated by polyamine-enhanced translational frameshifting.
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Background References:
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- Grimwood J., Gordon L.A.Nature 428:529-535(2004)
- Hayashi T., Matsufuji S.Gene 203:131-139(1997)
- Tewari D.S., Qian Y.Biochim. Biophys. Acta 1209:293-295(1994)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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