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Catalog #
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Source:
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Lot #
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Size:
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AP7597d
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Rabbit
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SA090225AH
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_055492, Q9UQ26
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RB16629
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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160403 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S427 of human RIMS2.
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Other Names:
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Regulating synaptic membrane exocytosis protein 2; Rab3-interacting molecule 2; RIM 2; RIMS2; KIAA0751, RAB3IP3, RIM2
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Application Data:
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Western blot analysis of anti-Phospho-RIMS2-S427.ctrl Pab (Cat.#AP7597d) in CEM cell line lysates (35ug/lane). Phospho-RIMS2-S427.ctrl(arrow) was detected using the purified Pab. |
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Background:
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RIMS2 is a Rab effector involved in exocytosis. It may act as a scaffold protein. The mature cytomatrix at the active zone (CAZ) of the synapse is defined by a set of multidomain proteins that harbor several proteinprotein or proteinlipid interaction domains. The complete protein composition of the CAZ is not known to date, but it includes the proteins RIMs, Munc13-1, ERC/CAST, Piccolo/Aczonin and Bassoon. RIMs are presynaptic active zone proteins that regulate Ca2+ triggered release of neurotransmitters.
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Background References:
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- Imami K., Anal. Sci. 24:161-166(2008).
- Wang Y., Genomics 81:126-137(2003).
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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