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Catalog #
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Source:
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Lot #
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Size:
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AT1425a
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mouse
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200 uL
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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4D12
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IgM Kappa
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Applications:
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Reactivity:
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MW:
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ELISA,WB-Ce,WB-Re
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H
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41915 Da
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Target/Specificity:
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CCR2 (-, 1 a.a. ~ 43 a.a) partial recombinant protein with GST tag.
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Other Names:
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CC-CKR-2, CCR2A, CCR2B, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R chemokine (C-C motif) receptor 2
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Application Data:
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CCR2 monoclonal antibody (M01A), clone 4D12 Western Blot analysis of CCR2 expression in HepG2 ( Cat # L019V1 ). |
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Background:
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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| ELISA | 1ug/ml~3ng/ml |
| Western blot | 1:500~1000 |
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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