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Catalog #
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Source:
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Lot #
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Size:
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AT1932a
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mouse
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08088
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0.1mg
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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NP_000112
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3F6
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IgG2b Kappa
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Applications:
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Reactivity:
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MW:
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ELISA,WB-Ce,WB-Re
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H
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55065 Da
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Target/Specificity:
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EPOR (NP_000112, 31 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Other Names:
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MGC138358erythropoietin receptor
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Application Data:
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EPOR monoclonal antibody (M02), clone 3F6. Western Blot analysis of EPOR expression in HeLa ( Cat # L013V1 ). |
Detection limit for recombinant GST tagged EPOR is approximately 0.03ng/ml as a capture antibody. |
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Background:
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The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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| ELISA | 1ug/ml~3ng/ml |
| Western blot | 1:500~1000 |
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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