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H2AFX monoclonal antibody (M17)
Purified Mouse Monoclonal Antibody (Mab)

Catalog # Source: Lot # Size:
AT2307a mouse 0.1mg
Type: Accession: Clone Name: Isotype:
Mab AAH11694 2H5 IgG2a Kappa
Applications: Reactivity: MW:
ELISA,S-ELISA H 15145 Da
Target/Specificity:
H2AFX (AAH11694, 1 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Other Names:
H2A.X, H2A/X, H2AX H2A histone family, member X
Application Data:

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Background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
Background References:
Product Citations:
Application Notes:
ELISA1ug/ml~3ng/ml
Format:
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Storage:
For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Precautions:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.