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Catalog #
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Source:
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Lot #
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Size:
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AT2757a
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mouse
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0.1mg
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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AAH07330
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6G7
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IgG1 Kappa
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Applications:
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Reactivity:
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MW:
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ELISA,S-ELISA
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H
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620418 Da
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Target/Specificity:
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MACF1 (AAH07330, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Other Names:
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ABP620, ACF7, FLJ46776, KIAA0465, KIAA1251, MACF, OFC4
microtubule-actin crosslinking factor 1
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Application Data:
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Detection limit for recombinant GST tagged MACF1 is approximately 1ng/ml as a capture antibody. |
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Background:
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The protein encoded by this gene belongs to the plakin family of cytoskeletal linker proteins. This protein family forms bridges between different cytoskeletal elements through specialized modular domains. The encoded protein is one of the largest size proteins identified in human cytoskeletal proteins. It has functional actin and microtubule binding domains, and it appears to stabilize actin at sites where microtubules and microfilaments meet. It may function in microtubule dynamics to facilitate actin-microtubule interactions at the cell periphery and to couple the microtubule network to cellular junctions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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