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Catalog #
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Source:
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Lot #
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Size:
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AT3183a
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mouse
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0.1mg
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Type:
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Accession:
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Clone Name:
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Isotype:
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Mab
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AAH37545
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3G4
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IgG2a Kappa
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Applications:
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Reactivity:
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MW:
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ELISA,IF,S-ELISA,WB-Ce,WB-Re
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H
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113084 Da
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Target/Specificity:
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PARP1 (AAH37545, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Other Names:
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ADPRT, ADPRT1, PARP, PARP1, PPOL, pADPRT1
poly (ADP-ribose) polymerase family, member 1
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Application Data:
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Immunofluorescence of monoclonal antibody to PARP1 (AT3183a) on HeLa cell . [antibody concentration 10 ug/ml] |
PARP1 monoclonal antibody (M01), clone 3G4 Western Blot analysis of PARP1 expression in HeLa NE ( Cat # L013V3 ). |
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Background:
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This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq]
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Background References:
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Product Citations:
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Application Notes:
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| ELISA | 1ug/ml~3ng/ml |
| Western blot | 1:500~1000 |
| Immunofluorescence | |
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Format:
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Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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Storage:
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For continuous use, store at 2-8°C for one-two days. For extended storage, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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